Cardiome Partner Eddingpharm to Initiate BRINAVESS Phase I Study in China

NASDAQ: CRME   TSX: COM

VANCOUVER, July 24, 2015 /CNW/ - Cardiome Pharma Corp. (NASDAQ: CRME /TSX: COM) today announced that its Chinese development and commercialization partner, Eddingpharm, plans to initiate a Phase 1 study for BRINAVESS^TM to support regulatory approval in China.  The study will be conducted in healthy volunteers. Other details of the study were not disclosed. If BRINAVESS successfully completes Phase 1, Eddingpharm anticipates initiating a pivotal Phase 3 study by year end.

"We are pleased that Eddingpharm is taking the first steps necessary to gain approval of BRINAVESS in China", said William Hunter, M.D., CEO and Director of Cardiome. "The Chinese market is an important growth driver for BRINAVESS given the region's size and demand for innovative medicines, and Eddingpharm is the perfect partner for Cardiome. Cardiome remains committed to have BRINAVESS available for all patients suffering from atrial fibrillation worldwide."

Cardiome and Eddingpharm entered into a BRINAVESS development and commercialzation agreement in China, Taiwan, Macau and Hong Kong on December 19, 2014. Under the terms of the agreement, Eddingpharm made an upfront payment of US $1.0M to Cardiome and agreed to specific annual commercial goals for BRINAVESS. Cardiome is also eligible to receive regulatory milestone payments of up to US $3.0M. Other financial details have not been disclosed.     

About Cardiome Pharma Corp.
Cardiome Pharma Corp. is a specialty pharmaceutical company dedicated to the development and commercialization of cardiovascular therapies that will improve the quality of life and health of patients suffering from heart disease. Cardiome has two marketed, in-hospital, cardiology products, BRINAVESS^TM (vernakalant IV), approved in Europe and other territories for the rapid conversion of recent onset atrial fibrillation to sinus rhythm in adults, and AGGRASTAT® (tirofiban HCl) a reversible GP IIb/IIIa inhibitor indicated for use in patients with acute coronary syndrome. Cardiome also commercializes Esmocard® and Esmocard Lyo® (esmolol hydrochloride), a short-acting beta-blocker used to control rapid heart rate in a number of cardiovascular indications, on behalf of their partner AOP Orphan Pharma in select European markets. Cardiome has also licensed TREVYENT, a development state drug device combination that is under development for Pulmonary Arterial Hypertension, for Europe, the Middle East and for Canadian markets.

Cardiome is traded on the NASDAQ Capital Market (CRME) and the Toronto Stock Exchange (COM). For more information, please visit our web site at www.cardiome.com.

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SOURCE Cardiome Pharma Corp.

David Dean, Cardiome Investor Relations, [phone] ext 311 or Toll Free: 1-800-330-9928, Email: [email protected]