MEZADVICE(TM)* helps patients stay on track

/NOT FOR DISTRIBUTION TO U.S. MEDIA/

Shire Canada Inc. ("Shire Canada ") introduces new refill reminder service for patients taking MEZAVANT(R)(xx)

MONTRÉAL, Nov. 17 /CNW/ - In an effort to help patients stay on track with their medication, Shire Canada has introduced MEZADVICE, an online refill reminder service for patients who have been prescribed MEZAVANT.

For any treatment to be effective, patients must take their medication as prescribed by their doctor. In many cases patients stop taking their medication as soon as their disease symptoms lessen or when their prescription runs out. This often leads to a reduction in the efficacy of their medication.

Now, Canadians prescribed MEZAVANT will be able to receive convenient reminders either by phone, email or SMS text message.

"Our goal with MEZADVICE is to provide reassurance and support to patients who have been prescribed MEZAVANT," states Claude Perron , Vice-President and General Manager, Shire Canada . "With help from MEZADVICE, Canadians prescribed MEZAVANT will be able to more easily keep track of when they need to refill their prescription, with the goal to promote adherence and better treatment outcome. We hope that with this new service, patients are better informed and enabled to be more proactive in successfully managing their disease."

About Shire plc & Shire Canada Inc.

Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases as well as opportunities in other therapeutic areas to the extent they arise through acquisitions. Shire's in-licensing, merger and acquisition efforts are focused on products in specialist markets with strong intellectual property protection and global rights. Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.

Shire Canada Inc. is a subsidiary of Shire plc. Shire Canada Inc.'s operations are headquartered in Montréal, Québec.

For further information on Shire, please visit the Company's Web site: www.shire.com

    
    *    MEZADVICE is a trade-mark of Shire Canada Inc.
    (xx)   MEZAVANT is a registered trade-mark used under licence from
           Giuliani International Limited
    

For further information: Chrome Communications, T: [phone] or Toll Free: 1-888-867-1406; Alon Barmapov, ext. 223, C: [phone], [email protected]; Amanda Webster, ext. 222, C: [phone], [email protected]