MilliporeSigma Wins Two R&D 100 Awards for Innovation in 2018

- BioReliance^® Viral and Gene Therapy Assay Portfolio wins award in Analytical/Test category

- MilliporeSigma's proxy-CRISPR wins Special Recognition Market Disruptor — Products award

BURLINGTON, Mass., Nov. 27, 2018 /CNW/ -- MilliporeSigma today announced that it has won two R&D 100 Awards. The 56^th annual R&D 100 Awards program, honoring the 100 most innovative and significant technologies introduced in the past year, recognized MilliporeSigma for its BioReliance^® Viral and Gene Therapy Assay Portfolio and proxy-CRISPR technology. MilliporeSigma has received nine R&D 100 Awards in the past six years.

Michelle Ding, R&D scientist at Merck, and Joanne Worobec, product marketing manager at Merck, accept the company's R&D 100 Awards at a ceremony held recently in Orlando, Florida. The R&D 100 Awards program identifies and celebrates the top 100 revolutionary technologies of the past year, spanning industry, academia and government-sponsored research.

"We are honored to receive two R&D 100 Awards, one recognizing our continuous focus on making gene therapy more widely accessible to patients in need by developing and implementing our BioReliance^® Viral and Gene Therapy assays rapidly," said Udit Batra, CEO, MilliporeSigma. "The second award highlights MilliporeSigma as a market leader in gene editing — the result of our longstanding R&D focus on CRISPR technology. I am immensely proud of our teams, who, every day, live our purpose to solve the toughest problems in life science."

MilliporeSigma's BioReliance^® Viral and Gene Therapy Assay Portfolio won a R&D 100 Award in the Analytical/Test category. The BioReliance^® Viral and Gene Therapy Assay Portfolio is a platform of assays that allows the timely release of viral and gene therapy vectors, cutting testing time nearly in half, while providing accurate and reliable results. MilliporeSigma developed the assays specifically for viral gene therapy product characterization, purity, potency, safety and release testing.

MilliporeSigma's proxy-CRISPR technology won a Special Recognition Market Disruptor — Products award. Market disruptor awards are given to those that have the potential to be "game changers," disrupting established technologies and transforming their respective industry.

Proxy-CRISPR is a new genome-editing tool for improving the performance of other newly discovered CRISPR proteins. This technology makes CRISPR more efficient, flexible and specific by opening up the DNA helix so researchers can make targeted sequence changes in previously inaccessible regions of the genome. MilliporeSigma's proxy-CRISPR provides a rapid and simple method to increase usability without the laborious need to re-engineer native CRISPR proteins.

The R&D 100 Awards are among the most prestigious innovation awards, honoring research and development pioneers.

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About the Life Science Business of Merck KGaA, Darmstadt, Germany
The Life Science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada, has 20,000 employees and 60 manufacturing sites worldwide, with a portfolio of more than 300,000 products enabling scientific discovery. Udit Batra is the global chief executive officer of MilliporeSigma.

Merck KGaA, Darmstadt, Germany completed its $17 billion acquisition of Sigma-Aldrich in November 2015, creating a leader in the $125 billion global life science industry.

Merck KGaA, Darmstadt, Germany, the vibrant science and technology company, operates across healthcare, life science and performance materials. Around 53,000 employees work to make a positive difference to millions of people's lives every day by creating more joyful and sustainable ways to live. From advancing gene-editing technologies and discovering unique ways to treat the most challenging diseases to enabling the intelligence of devices – the company is everywhere. In 2017, Merck KGaA, Darmstadt, Germany generated sales of €15.3 billion in 66 countries.

The company holds the global rights to the name and trademark "Merck" internationally. The only exceptions are the United States and Canada, where the business sectors of Merck KGaA, Darmstadt, Germany operate as EMD Serono in healthcare, MilliporeSigma in life science, and EMD Performance Materials. Since its founding 1668, scientific exploration and responsible entrepreneurship have been key to the company's technological and scientific advances. To this day, the founding family remains the majority owner of the publicly listed company. For more information about Merck, KGaA, Darmstadt, Germany, visit www.emdgroup.com.

SOURCE MilliporeSigma

Karen Tiano [phone]